Quinolines and derivatives
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Filtered Search Results
Ambeed AMBEED
5000868456 1-QUINOLIN-2-YLETHANONE 1GR
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Ambeed AMBEED
5000868263 6-BROMOQUINOLINE-2-CARBOXY 1GR
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Ambeed AMBEED
5000869876 23-DIBROMOPROPAN-1-AMINE H 1GR
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Ambeed AMBEED
5000868247 5-ETHYLPYRIDIN-2-AMINE 1GR
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000431159 CYANINE5.5 AMINE 5MG
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Ambeed AMBEED
5000866871 M-PEG12-AMINE 100MG
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TARGETMOL CHEMICALS INC DHODH-IN-13 5MG
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Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. DHODH-IN-13 is an inhibitor of DHODH with IC50 of 4.3 uM for rat liver. DHODH-IN-13 can be used in studies about rheumatoid arthritis. purity: 99%
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Apexbio Technology LLC MCC950 sodium(Synonyms: CP-456773 sodium, CRID3 sodium, MCC-950 sodium, MCC950 sodium salt), 200mg, CAS: 256373-96-3.
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MCC950 sodium (CAS 256373-96-3) is a selective small-molecule inhibitor targeting the NOD-like receptor family protein 3 (NLRP3) inflammasome MCC950 sodium inhibits NLRP3 activation in murine bone marrow-derived macrophages (BMDMs) with an IC50 of 7 5 nM and demonstrates comparable selectivity and potency in human monocyte-derived macrophages (HMDMs) It specifically blocks both canonical and noncanonical activation pathways without affecting other inflammasomes such as AIM2 NLRC4 and NLRP1 Due to its selectivity MCC950 sodium is valuable in investigating NLRP3-associated inflammatory and autoimmune conditions
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TARGETMOL CHEMICALS INC PF-04979064 25MG
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Also available in 2 mg 5 mg 10 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. PF-04979064 is a potent and selective PI3K and mTOR dual kinase inhibitor(Ki of 0.13 nM and 1.42 nMrespectively). purity: 98%
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Medchemexpress LLC Sulfo-EGS 10mg | 167410-92-6 | 10 MG
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Sulfo-EGS is a water-soluble, homobifunctional, amine-reactive crosslinker used to covalently link proximal primary amines in proteins and peptides to map interactions and probe complex topology. It is provided for research use in small milligram quantities.
- Water-soluble homobifunctional amine-reactive crosslinker.
- Targets primary amines for covalent crosslinking of proteins and peptides.
- Facilitates mapping of protein-protein and protein-peptide interactions.
- Suitable for small-scale, solution-phase crosslinking experiments.
- Available in milligram pack sizes for research applications.
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Medchemexpress LLC 3-sulfo-taurocholic acid disodium salt | 71781-33-4 | 99.0% | 639.73 | C26H43NNa2O10S2 | 1mg
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3-Sulfo-taurocholic Acid Disodium Salt (3-Sulfocholyl Taurine TCA3S) is a metabolite of the conjugated bile acid taurocholic acid Plasma levels of 3-Sulfo-taurocholic Acid Disodium Salt are elevated in wild-type and Sortilin 1 (Sort1) knockout mice at 6 hours following bile duct ligation (BDL) and are further elevated in Sort1 knockout mice at 24 hours post-BDL
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Medchemexpress LLC 2,8-Quinolinediol | 15450-76-7 | 99.7% | 161.16 | 25 G
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8-Hydroxy-2(1H)-quinolinone is a biochemical reagent that can be used as a biological material or organic compound for life science-related research. This product is for research use only and has not been fully validated for medical applications.
- Suitable for life science-related research
- Can be used as a biological material or organic compound
- Powder storage: -20°C for 3 years, 4°C for 2 years
- In solvent storage: -80°C for 6 months, -20°C for 1 month
- Soluble in DMSO at 20 mg/mL (124.10 mM) with ultrasonic, warming, and heating to 60°C
- Forms clear solutions (≥ 2 mg/mL) in common in vivo dissolution protocols
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Apexbio Technology LLC Amisulpride 71675-85-9 200mg
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Amisulpride is a small-molecule antagonist targeting dopamine D2 and D3 receptor subtypes It is designed to inhibit dopamine-mediated receptor activation thereby modulating dopaminergic signaling pathways Amisulpride exerts its biological activity primarily through antagonism of dopamine receptors In radioligand binding assays using rat striatal D2 autoreceptors and limbic brain regions amisulpride demonstrates high binding affinity with Ki values of approximately 2 8 nM (D2) and 3 2 nM (D3) Additionally it inhibits dopamine agonist-induced cellular responses such as quinpirole-stimulated thymidine incorporation Based on these pharmacological properties amisulpride holds research potential in dopamine receptor-related neurochemical research and investigations of dopaminergic signaling pathways
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Medchemexpress LLC Romaciclib monohydrochloride | 2443816-41-7 | 99.3% | 450.60 | 50 MG
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Romaciclib monohydrochloride is an ATP-competitive and selective CDK8 inhibitor, inhibiting kinase activities of CDK8/CycC and CDK19/CycC complexes. It weakly inhibits CDK9 but shows no obvious activity against CDK1, 2, 4, 6, 5, 7. This compound inhibits phosphorylation of STAT1 S727 and STAT5 S726 and has anti-tumor activity. It is for research use only.
- Inhibits kinase activities of CDK8/CycC and CDK19/CycC complexes.
- Weakly inhibits CDK9.
- Shows no obvious activity against CDK1, 2, 4, 6, 5, 7.
- Inhibits phosphorylation of STAT1 S727 and STAT5 S726.
- Has anti-tumor activity.
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Medchemexpress LLC Amisulpride | 71675-85-9 | MFCD00866691 | 99.8% | C17H27N3O4S | 200 MG
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Amisulpride is a racemic (50:50) mixture of R-Amisulpride and S-Amisulpride. It acts as a dopamine D2/D3 receptor antagonist with Ki values of 2.8 nM for human dopamine D2 and 3.2 nM for human dopamine D3 receptors. Amisulpride also functions as a 5-HT7 receptor antagonist with a Ki of 44 nM, making it suitable for use in psychiatric research.
- Racemic mixture
- Dopamine D2/D3 receptor antagonist
- 5-HT7 receptor antagonist
- Suitable for psychiatric research
- D3 receptor Ki: 3.2 nM
- Human D2 receptor Ki: 2.8 nM
- 5-HT7 receptor Ki: 44 nM
- Inhibits quinpirole-elicited [3H]thymidine incorporation
- Increases dopamine release from rat striatum slices
- Increases dopamine synthesis in rat striatum and limbic system
- Increases extracellular dopamine levels
- Decreases striatal ACh levels
- Increases duration of swimming behavior
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